Yes. The OxyGo NEXT is approved by the FAA (Federal Aviation Administration) for use on an airplane. To confirm, you can look on the back or bottom of your unit for a sticker that looks like the following:
Example of an FAA-approval label. It may vary from make to model.
But, just because your POC is approved for in-flight use, you still need to be aware of other FAA, TSA, and airline requirements. Check out our blog post Can I fly with my portable oxygen concentrator for more information on flying with your POC.